(43) Submitted.
​
(42) T.S. Teitsworth*, L. Rotundo, H. Fang, M. Tanwar, T. Robinson, D.J. Siegel, R.E. Powers, A.D. Orr, A.K. Harvey, R.N. Sampaio, C.L. Donley, J.M. Atkin, J.L. Dempsey, Z. Fakhraai, G. Manbeck, S.J. Tereniak, and M.R. Lockett* (2025) Potential-controlled deposition of multilayer CO2 reduction catalyst films on silicon photoelectrodes demonstrates thickness-dependent catalytic rates. ACS Applied Mater. Interfaces. accepted. 

(41) A.D. Orr, Z. Zhu, N. Durand, A. Bonfiglio, T.S. Teitsworth, R.N. Sampaio, F.N. Casellano, J.F. Cahoon, C.L Donley, and MR. Lockett* (2025) Immobilizing a Lehn-type catalyst with nitrocyclocondensation chemistries: CO2 reduction on silicon hybrid photoelectrodes. ACS Applied Mater. Interfaces. accepted. 
*Check out this UNC write-up on our paper*

​(40) R.A. Lidgett, A.A. Miranda Buzetta, J.I. Baker, A.L. Oldenburg, and M.R. Lockett* (2025) Analytical Screening Platform to Differentiate Acute and Prolonged Exposures of PFAS on Invasive Cellular Phenotypes. Toxicol. Sci. accepted. 
*Check out this UNC write-up on our paper*

(39) S. He, S. Bottum, J. Dickenson, H. Margavio, N. Keller, O. Oyetade, R. Gentile, T.S. Teitsworth, S.J. Shin, J. Dempsey, A. Miller, R. Sampaio, S. Tereniak, C. Donley, M.R. Lockett, G. Parsons, G. Meyer, and J. Cahoon* (2025) Electron inversion and tunneling at silicon thermal oxide interfaces for solar-driven molecular catalysis to syngas. JACS. accepted.

(38) T.S. Teitsworth, H. Fang, A.K. Harvey, A.D. Orr, C.L. Donley, Z. Fakhraai, J.M. Atkin, and M.R. Lockett* (2024) Diazonium-functionalized silicon hybrid photoelectrodes: Film thickness and composition effects on photelectrochemical behavior. Langmuir. 

(37) L. Yang, P. Ji, A.A. Miranda Buzetta, H. Li, M.R. Lockett, H. Zhou, and A.L. Oldenburg* (2024) Longitudinal tracking of perfluoroctanoic acid exposure on mammary epithelial cells spheroids by dynamic optical coherence tomography. Biomed. Opt. Express.

(36) Z.R. Sitte, E.E. Karlsson #, H. Lin, H. Zhou, and M.R. Lockett* (2024) Continuous flow delivery system for the perfusion of scaffold-based 3D cultures. Lab Chip.

(35) Z.R. Sitte, E.E. Karlsson #, T.S. Larson, H. Lin, H. Zhou, and M.R. Lockett* (2024) Supported gel slab scaffolds as a three-dimensional cell-based assay platform. Analyst. 
​
(34) Z.R. Sitte, A.A. Miranda Buzetta, T.J. DiProspero, and M.R. Lockett* (2024) A three-zone hypoxia chamber capable of regulating unique oxygen and carbon dioxide partial pressures simultaneously. Hardware X. 

(33) T.S. Larson, T.J. DiProspero, G.L. Glish*, and M.R. Lockett* (2024) Differential lipid analysis of oxaliplatin and resistant HCT116 cells reveals different levels of drug-induced lipid droplet formation. Anal. Bioanal. Chem.
​
(32) Z.R. Sitte, A.A. Miranda Buzetta, S.J. Jones, Z.W. Lin #, N.A. Whitman, and M.R. Lockett* (2023) Paper-based co-culture platform to evaluate the effects of fibroblasts on estrogen signaling in ER+ breast cancers. ACS Meas. Sci. Au.  

(31) T.S. Larson, C. Worthington, M. Verber, J. Keating, and M.R. Lockett*, G.L. Glish* (2023) DiffN selection of tandem mass spectrometry precursors. ​Anal. Chem.

(30) Z.R. Sitte, T.S. Larson, J.C. McIntosh, M. Sinanian, and M.R. Lockett* (2023) Selecting the appropriate indirect viability assay for 3D paper-based cultures: A data-driven study. Analyst. 

​(29) S.R. Bottum, T.S. Teitsworth, Q. Han, A.D. Orr, J.S. Park, X. Jia, C. Cappuccino, B.H. Layne, N. Hazari, J.J. Concepcion, C.L. Donley, D.E. Polyansky, M.R. Lockett, J.F. Cahoon*, and D.C. Grills* (2023) In situ attenuated total reflectance infrared spectroelectrochemistry (ATR-IR-SEC) for the characterization of molecular redox processes on surface-proximal doped silicon ATR crystal working electrodes. J. Phys. Chem. C.  

(28) R.M. Kenney, M.C. Lee #, M.W. Boyce, Z.R. Sitte, and M.R. Lockett* (2023) Cellular invasion assay for the real-time tracking of individual cells in spheroid or tumor-like mimics. Anal. Chem.
​
(27) X. Jia, H.S. Nedzballa, S.R. Bottum, J.F. Cahoon, J.J. Concepcion*, C.L. Donley, A. Gang, Q. Han, N. Hazari*, M.R. Lockett, J.M. Mayer*, B.Q. Mercado, G.J. Meyer, A.J. Pearce, C.L. Rooney, R.N. Sampaio, B. Shang, and H. Wang (2023). Synthesis and surface attachment of molecular Re(I) complexes supported by functionalized bipyridyl ligands.  Inorg. Chem. 

(26) Z.R. Sitte, T.J. DiProspero, and M.R. Lockett* (2023). Evaluating the impact of physiological oxygen tensions on drug metabolism in 3D hepatocyte cultures. Curr. Protocol Toxicol. 

(25) T.J. DiProspero, L.G Brown #, T.D. Fachko #, and M.R. Lockett* (2022). HepaRG cells adopt zonal-like drug-metabolizing phenotypes under physiologically relevant oxygen tensions and Wnt/b-catenin signaling. Drug Metab. Dispos., 50. 1098-1105.
​
(24) T.S. Larson, G.L. Glish*, and M.R. Lockett* (2021). Spatially resolved quantification of drug metabolism and efficacy in 3D paper-based tumor mimics. Anal. Chim. Acta, 118. 339091. 

(23) T.J. DiProspero, E. Dalrymple #, and M.R. Lockett* (2021). Physiologically relevant oxygen tensions differentially regulate hepatotoxic responses in HepG2 cells. Toxicol. In Vitro, 74. 105156.

(22) D. Dhar^, C.G. McKenas^, C.W. Huang, J.M. Atkin,* J.L. Dempsey*, and M.R. Lockett* (2020). ​Quantitative effects of disorder on chemically modified amorphous carbon electrodes. ACS Appl. Energy Mater., 3 (8). 8038-8047. 

(21) J.C. McIntosh ^, L. Yang ^, T. Wang, H. Zhou, M.R. Lockett*, and A.L. Oldenburg* (2020). Tracking the invasion of breast cancer cells in paper-based 3D cultures by OCT motility analysis. Biomed. Opt. Express. 11. 3181-3194.​

(20) M.W. Boyce^, W.C. Simke^, R.M. Kenney, and M.R. Lockett* (2020). Generating linear oxygen gradients across 3D cell cultures with Block-Layered Oxygen Controlled Chips (BLOCCs). Anal. Methods, 12. 18-24.
​
(19) ​F. Tobias, J.C. McIntosh, G.J. LaBonia, M.W. Boyce, M.R. Lockett, and A.B. Hummon* (2019). Developing a drug screening platform: MALDI-mass spectrometry imaging of paper-based cultures. Anal. Chem. 91. 15370-15376.

(18) S.M. Cramer, T.S. Larson, and M.R. Lockett* (2019) Tissue papers: Leveraging paper-based microfluidics for the next generation of 3D tissue models. Anal. Chem., 19. 10916-10926.

(17) N.A. Whitman, Z.W. Lin #, R.M. Kenney, L. Albertini, and M.R. Lockett* (2019) Hypoxia differentially regulates estrogen receptor alpha in 2D and 3D culture formats. Arch. Biochem. Biophys., 678. 8-17.

(16) P.R. Graves, L.J. Aponte-Collazo, E.M.J. Fennell, A.C. Graves, A.E. Hale, N. Dicheva, L.E. Herring, T.S.K. Gilbert, M.P. East, I.M. McDonald, M.R. Lockett, H. Ashamalia, N.J. Moorman, D.S. Karanewsky, E.J. Iwanowicz, E. Holmunhamedov, L.M. Graves (2019) Mitochondrial protease ClpP is a target for the anticancer compounds ONC201 and related analogs. ACS Chem. Biol., 14. 1020-1029.

(15) J.M. Fehr# ^, C.G. McKenas ^, B. Liu#, and M.R. Lockett* (2019). ​Azide-alkyne click reactions to prepare chemically modified amorphous carbon electrodes. Appl. Surf. Sci., 480. 1109-1115.​

(14) ​R.M. Kenney, A. Loeser#, N.A. Whitman, and M.R. Lockett* (2019). ​​Paper-based transwell assays: An inexpensive alternative to study cellular invasion. Analyst, 144. 206-211.

(13) ​N.A. Whitman, Z.W. Lin#, T.J. DiProspero, J.C. McIntosh, and M.R. Lockett* (2018). Screening estrogen receptor modulators in a paper-based breast cancer model. Anal. Chem., 90. 11981-11988.

​(12) C.G. McKenas, J.M. Fehr#, B. Liu#, C.L. Donley, and M.R. Lockett* (2018). ​Mechanistic insights into UV-initiated thiol-ene reactions on amorphous carbon films. J. Phys. Chem. C​, 138. 21854-21860.
​
(11) R.M. Kenney, M.W. Boyce, N.A. Whitman, B.P. Kromhout, and M.R. Lockett* (2018). A pH-sensing optode for mapping spatiotemporal gradients in 3D paper-based cell cultures. Anal. Chem., 90. 2376-2383.

(10) M.W. Boyce, G. Labonia, A.B. Hummon, and M.R. Lockett* (2017). Assessing chemotherapeutic effectiveness using a paper-based tumor model. Analyst, ​142. 2819-2827.

(9) R.M. Kenney, C.C. Lloyd, N.A. Whitman, and M.R. Lockett* (2017). 3D cellular invasion platforms: How do paper-based cultures stack up?. Chemical Communications, 53. 7194-7210.
​(Special issue invitation: 2017 Emerging Investigators) 

(8) C.C. Lloyd, M.W. Boyce, and M.R. Lockett* (2017). Paper-based invasion assay for quantifying cellular movement in three-dimensional tissue-like structures. Current Protocols in Chemical Biology, 9(1). 1-20.

​(7) C.G. McKenas, J.M. Fehr#, C.L. Donley, and M.R. Lockett* (2016). ​Thiol-ene modified amorphous carbon substrates: surface patterning and chemically modified electrode preparation. Langmuir, 32(41). 10529-10536.

(6) A.S. Truong and M.R. Lockett* (2016). Oxygen as a chemoattractant: Confirming cellular hypoxia in paper-based invasion assays. Analyst, 141(12). 3874-3882. 
(Special issue invitation: Emerging Investigators)

​(5) N.A. Whitman, J.C. McIntosh, J.B. Penley#, and M.R. Lockett* (2016). Microfabricated Devices for Studying the Metabolism and Cytotoxicity of Drug Candidates. Curr. Pharm. Biotechnol., 17(9). 755-771.
(Special issue invitation: Miniaturized Platforms and Methods for Pharmaceutical Studies)

​(4) M.W. Boyce, R.M. Kenney, A.S. Truong, and M.R. Lockett* (2016) Quantifying oxygen in paper-based cell cultures with luminescent thin film sensors. Anal. Bioanal. Chem., 408(11). 2985-2992.
(Special issue invitation: Young Investigators)

(3) ​R.M. Kenney, M.W. Boyce, A.S. Truong, C.R. Bagnell, and M.R. Lockett* (2016) Real-time imaging of cancer cell chemotaxis in paper-based scaffolds. Analyst, 141(2). 661-668.
(Special issue invitation: Cancer Detection and Diagnosis)

​(2) A.S. Truong, C.A. Lochbaum#, M.W. Boyce, and M.R. Lockett* (2015) Tracking the invasion of small numbers of cells in paper-based assays with quantitative PCR. Anal. Chem., 87(22). 11263-11270.

​(1) M.R. Lockett* and L.M. Smith* (2015) Carbon substrates: A stable foundation for biological arrays. Annu. Rev. Anal. Chem., 8(1). 

Prior to independent career

 * indicates co-authorship

(cc) K.A. Simon, B. Mosadegh, K.T. Minn, M.R. Lockett, M.R. Mohammady, D.M. Boucher, A.B. Hall, S. Hillier, T. Udagawa, B.K. Eustace, and G.M. Whitesides (2016). Metabolic response of lung cancer cells to radiation in a paper-based 3D cell culture system, Biomaterials, 95 (1). 47-59.

(bb) J.M. Fox, K. Kang, W. Sherman, A. Heroux, M. Sastry, M. Baghbanzadeh, M.R. Lockett, and G.M. Whitesides (2015) Interactions between Hofmeister anions and the binding pocket of a protein, J. Am. Chem. Soc., 137 (11). 3859-3866.

(aa) B. Mosadegh,* M.R. Lockett,* K.T. Minn, K.A. Simon, K. Gilbert, S. Hillier, D. Newsome, H. Li, A.B. Hall, D.M. Boucher, B.K. Eustace, and G.M. Whitesides (2015) A Paper-based invasion assay: Assessing the metastatic potential of cancer cells in gradients of oxygen, Biomaterials, 52 (1). 262-271.

(z) H.J. Yoon, K.C. Liao, M.R. Lockett, S.W. Kwok, M. Baghbanzadeh, and G.M. Whitesides (2014) Rectification in tunneling junctions: 2,2'-bipyridyl-terminated n-alkanethiolates, J. Am. Chem. Soc., 136 (49). 17155-17162.

(y) B. Mosadegh, B.E. Dabiri, M.R. Lockett, R. Derda, P. Campbell, K.K. Parker, and G.M. Whitesides (2014) Three-dimensional paper-based model for cardiac ischemia, Adv. Healthcare Mat., 3 (7). 1036-1043. 

(x) P.W. Snyder,* M.R. Lockett,* D.T. Moustakas, and G.M. Whitesides (2014) Is it the shape of the pocket, or the shape of water within the pocket?, Eur. J. Phys. Spec. Top., 223 (5). 853-891.

(w) B. Breiten,* M.R. Lockett,* W. Sherman, M. Al-Sayah, S. Fujita, H. Lange, C.M. Bowers, A. Heroux, G. Krilov, and G.M. Whitesides (2013) Water networks contribute to enthalpy/entropy compensation in protein-ligand binding, J. Am. Chem. Soc., 135 (41). 15579–15584.
​
(v) R. Derda,* M.R. Lockett,* S.K.Y. Tang, R.C. Fuller, E.J. Maxwell, B. Breiten, C.A. Cuddemi, A. Ozdogan, and G.M. Whitesides (2013) Filter-based assay for E. coli in aqueous samples using bacteriophage-based amplification. Anal. Chem., 85 (15). 7213-7220.

(u) M.R. Lockett,* H. Lange,* B. Breiten,* A. Heroux, W. Sherman, D. Rappoport, P.O. Yau, P.W. Snyder, and G.M. Whitesides (2013) The binding of benzoarylsulfonamide ligands to human carbonic anhydrase is insensitive to formal fluorination of the ligand, Angew. Chem., Int. Ed., 52 (30). 7714-7717.

(t) M.R. Lockett, K.M. Mirica, C.R. Mace, R. Blackledge, and G.M. Whitesides (2013) Analysis of forensic evidence based on density with magnetic levitation, J. Forens. Sci., 58 (1). 40-45.

(s) A.H. Broderick, M.C.D. Carter, M.R. Lockett, L.M. Smith, and D.M. Lynn (2013) Fabrication of oligonucleotide and protein arrays on rigid and flexible surfaces coated with reactive polymer multilayers, ACS Appl. Mater. Interfaces, 5 (2). 351-359.

(r) K.A. Mirica, M.R. Lockett, P.W. Snyder, N.D. Shapiro, and G.M. Whitesides (2012) Selective precipitation and purification of monovalent proteins using oligovalent ligands and ammonium sulfate, Bioconj. Chem., 23 (2). 293-299.

(q) C.H. Wu, M.R. Lockett, L.M. Smith (2012) RNA gene assembly from DNA arrays, Angew. Chem., Int. Ed., 51 (19). 4628-4632.

(p) A.H. Broderick,* M.R. Lockett,* M.E. Buck, Y. Yuan, L.M. Smith, and D.M. Lynn (2012) Layer-by-layer assembled films for the in-situ synthesis of oligonucleotide arrays, Chem. Mater., 24 (5). 938-945.

(o) P.W. Snyder, J. Mecinovic, D.T. Moustakas, S.W. Thomas, M. Harder, E.T. Mack, M.R. Lockett, A. Heroux, W. Sherman, and G.M. Whitesides (2011) The origin of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase, Proc. Natl. Acad. Sci. U.S.A., 108 (44). 17889-17894.

(n) C.N. Olson, M.M. Galloway, G. Yu, C.J. Hedman, M.R. Lockett, T.P. Yoon, E.A. Stone, L.M. Smith, and F.N. Keutsch (2011) Hydroxycarboxylic acid-derived organosulfates: Synthesis, stability and quantification in ambient aerosol, Environ. Sci. Technol., 45 (15). 6468-6474.

(m) M.R. Lockett and L.M. Smith (2010) Halogenation of carbon substrates for increased reactivity with alkenes, Langmuir, 26 (22). 16642-16646.

(l) M.R. Lockett and L.M. Smith (2010) The formation and stability of alkyl thiol monolayers on carbon substrates, J. Phys. Chem. C, 114 (29). 12635-12641.

(k) J.B. Mandir,* M.R. Lockett,* M.F. Phillips, H.T. Allawi, V.I. Lyamichev, and L.M. Smith (2009) Rapid Detection of RNA accessible sites by surface plasmon resonance detection of hybridization to DNA arrays, Anal. Chem., 81 (21). 8949-8956.

​(j) M.R. Lockett and L.M. Smith (2009) Fabrication and Characterization of DNA Arrays Prepared on Carbon-on-Metal Substrates, Anal. Chem., 81 (15). 6429-64037.

(i) M.R. Lockett, D.V. Le, J.C. Carlisle, and L.M. Smith (2009) Acyl chloride-modified amorphous carbon substrates for the attachment of alcohol-, thiol-, and amine-containing molecules, Langmuir, 25 (9). 5120-5126.

(h) M.R. Lockett and L.M. Smith (2009) Attaching molecules to chlorinated and brominated amorphous carbon substrates via Grignard reactions, Langmuir, 29 (6). 3340-3343.

(g) M.R. Lockett, M.R. Shortreed, and L.M. Smith (2008) Aldehyde terminated amorphous carbon surfaces for the fabrication of biomolecule arrays, Langmuir, 24 (17). 9198-9203.

(f) M.R. Lockett, S.C. Weibel, M.F. Phillips, M.R. Shortreed, B. Sun, R.M. Corn, R.J. Hamers, F. Cerrina, and L.M. Smith (2008)  Carbon-on-metal films for surface plasmon resonance detection of DNA arrays,  J. Am. Chem. Soc., 130 (27). 8611-8613.

(e) M.F. Phillips, M.R. Lockett, M.J. Rodesh, M.R. Shortreed, F. Cerrina, and L.M. Smith (2008) In situ oligonucleotide synthesis on carbon materials: stable substrates for microarray fabrication, Nucleic Acids Res., 36 (1). e7.

(d) M.R. Lockett, M.F. Phillips, J.L. Jarecki, D. Peelen, and L.M. Smith (2008) A tetrafluorophenyl activated ester self-assembled monolayer for the immobilization of amine-modified oligonucleotides, Langmuir, 24 (1). 69-75.

(c) M.R. Lockett, M. M.R. Shortreed, and L.M. Smith (2007) Molecular beacon-style hybridization assay for quantitative analysis of surface invasive cleavage reactions, Anal. Chem., 79 (15). 6031-6036.

(b) J. Lee, D. Didier, M.R. Lockett, M. Scalf, A.S. Greene, M. Olivier, and L.M. Smith (2007) Characterization of vascular endothelial growth factor (VEGF) receptors on the endothelial cell surface during hypoxia using whole cell binding assays, Anal. Biochem., 369 (2). 241-247.

(a) B. Sun, P.E. Colavita, H. Kim, M. Lockett, M.S. Marcus, L.M. Smith, and R.J. Hamers (2006) Covalent photochemical functionalization of amorphous carbon thin films for integrated real-time biosensing, Langmuir, 22 (23). 9598-9601.